A diabetic bulla is also known as "Bullosis diabeticorum" and "Bullous eruption of Diabetes Mellitus". It is a cutaneous condition characterized by a noninflammatory, spontaneous, painless blister, often in acral locations (peripheral body parts, such as feet, toes, hands, fingers, ears or nose), seen in diabetic patients. Specific treatment of bullous disease of diabetes (Bullosis diabeticorum) is unnecessary because the condition is self-limiting. The blister should be left intact whenever possible to serve as a sterile dressing and to avoid secondary infection. Drug therapy (that is; antibiotics) is only warranted when secondary staphylococcal infection is present. Other differential diagnoses to be considered in these cases are friction blisters, bullous fixed drug reactions, bullous pemphigoid, bullous SLE, and epidermolysis bullosa acquisita. Routine histopathological investigations of diabetic bullae show nonspecific features including an intraepidermal or subepidermal bulla.
- Track 1-1 Vesiculobullous Reaction Pattern
- Track 2-2 Dystrophic Epidermolysis Bullosa (DEB)
- Track 3-3 Junctional Epidermolysis Bullosa (JEB)
- Track 4-4 Epidermolysis Bullosa Simplex (EBS)
- Track 5-5 Epidermolysis Bullosa Simplex (EBS)
- Track 6-6 Bullous Pemphigoid
- Track 7-7 Bullous Solar Elastosis